Dalhousie University Department of Physiology & Biophysics  
  SIR CHARLES TUPPER MEDICAL BUILDING, HALIFAX, NOVA SCOTIA, CANADA B3H 4R2 | +1 (902) 494 3517  
 
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  Dr Evgeny Pavlov
Assistant Professor
MSc, Moscow State University (1995)
PhD, Inst. of Theor. and Exp. Biophysics, Russia (1999)

Email Evgeny.Pavlov@Dal.Ca
Phone +1 902 494 8980
Address 5850 College Street, Halifax, B3H 4R2, Nova Scotia, Canada

Research Interests
Cell death; Mitochondrial physiology; Metabolism and physiological roles of inorganic polyphosphate in mammalian organisms


 
Research program and experimental approaches

Research program in my lab is directed at better understanding the mechanisms of how mitochondria are involved in regulation of cell function under physiological as well as pathological conditions. More specifically we are interested in investigation of the roles of two mitochondrial biopolymers: inorganic polyphosphate and polyhydroxybutyrate. The central goal of our research is to study how these polymers are involved in regulation of cell metabolism and mitochondrial ion transport. In our work we use several experimental strategies: 1) We work with a number of cultured cell models of diseases in order to investigate how mitochondrial function is changed during stress conditions and how this affects the ability of the cells to survive; 2) We study mitochondrial physiology using isolated mitochondria; 3) We perform a wide range of biochemical quantitative assays of various mitochondrial compounds to study the link between their metabolism and mitochondrial function.



 
Lab members

Dr. Matthew Smithen, PhD, Research associate

Mrs. Pia Elustondo, Research assistant



 
Opportunities

We currently have research projects available for BSc Honours and summer students. Students interested in working on the projects related to the studies of mitochondrial physiology are encouraged to e-mail me directly at Evgeny.pavlov@dal.ca